01 - Preheat oven to 350°F. Grease a 9x5-inch loaf pan and line with parchment paper.
02 - Whisk together flour, baking powder, baking soda, and salt in a large bowl until well blended.
03 - In a separate bowl, combine Greek yogurt, granulated sugar, eggs, oil, lemon zest, lemon juice, and vanilla extract. Whisk until smooth and creamy.
04 - Pour wet ingredients into dry ingredients. Gently fold with a spatula until just combined, being careful not to overmix.
05 - Transfer batter to prepared loaf pan and smooth top. Bake for 45-55 minutes until a toothpick inserted in center comes out clean.
06 - Let cake cool in pan for 10 minutes, then remove to wire rack. Whisk powdered sugar with lemon juice until thick but pourable. Drizzle over cooled loaf.
07 - Slice loaf into 10 equal pieces and serve.