01 - Pat shrimp completely dry with paper towels, then season evenly with kosher salt and black pepper.
02 - Arrange three shallow bowls: combine flour, cornstarch, garlic powder, and smoked paprika in the first; place beaten eggs in the second; add panko breadcrumbs to the third.
03 - Dredge each shrimp in the flour mixture, shaking off excess. Dip into egg wash, allowing excess to drip off, then press firmly into panko to coat completely.
04 - Pour 2 inches of vegetable oil into a deep skillet or Dutch oven. Heat to 350°F, maintaining temperature throughout frying.
05 - Fry shrimp in batches for 2-3 minutes, turning halfway through, until golden brown and crispy. Transfer to paper-towel-lined plate to drain.
06 - In a small saucepan over low heat, melt butter with honey, hot sauce, and red pepper flakes. Whisk until fully combined and warmed through, about 2 minutes.
07 - Place fried shrimp in a large bowl, pour hot honey glaze over top, and toss gently until evenly coated. Serve immediately garnished with fresh herbs and lemon wedges.